The VITALIS article asserts that RCT evidence favors PUFAs over saturated fats and that patient shifts away from seed oils will accelerate cardiac harm. This claim rests on selective citation of older trials while ignoring reanalyses that found no cardiovascular mortality reduction. The Minnesota Coronary Experiment, when re-evaluated with recovered data, showed higher all-cause mortality in the linoleic acid arm (Ramsden et al., BMJ 2016). The Sydney Diet Heart Study similarly reported increased cardiovascular and all-cause deaths with PUFA substitution (Ramsden et al., BMJ 2013). Meta-analyses restricted to adequately controlled trials, such as those in the Cochrane Database (Hooper et al., 2020 update), find no clear reduction in clinical events once bias and incomplete reporting are addressed. Recent observational data from UK Biobank cohorts further indicate no protective association between higher omega-6 intake and reduced coronary outcomes after adjusting for overall diet quality.