The BBH-Genesis pipeline applied to GWTC-4, the largest gravitational-wave catalog yet released, uses hierarchical Bayesian inference on ~150 binary black hole events to test formation-channel hypotheses. The analysis favors a two-channel model with strong evidence, consistent with isolated binary evolution plus a non-isolated component, while a three-channel extension that includes active galactic nucleus (AGN) disks receives only mild support through subtle shifts in effective spin and mass-ratio distributions. This preprint (arXiv:2606.00234) correctly identifies the statistical separation of populations but underplays how the inferred sub-population aligns with supernova fallback prescriptions and pair-instability mass gaps already constrained by optical surveys such as those in the LIGO-Virgo-KAGRA collaboration's GWTC-3 catalog (arXiv:2111.03634). It also overlooks emerging multi-messenger links: the same AGN-disk channel invoked here could produce electromagnetic counterparts detectable by upcoming Rubin Observatory transients, a connection not addressed in the current modeling. Limitations include the reliance on simulated waveform templates that may bias spin measurements and the absence of redshift-dependent selection effects that future O5 runs will need to resolve. Overall, the work strengthens the case that binary black hole demographics encode both stellar evolution and dynamical environments, directly informing next-generation cosmology constraints from standard sirens.